Ru Rong Ji Lab

However, our understanding of sexual dimorphism in CIPN remains unclear.

Ru rong ji lab. Duke University Medical Center. Ru-Rong Ji from Duke University Medical Center. Long-Jun Wu invited and hosted the visit of Dr.

Chul-Kyu Park,1Zhen-Zhong Xu,1Tong Liu,1Ning Lü,1Charles N. From the Jackson Laboratory and maintained at the Duke University Animal Facility. Ru-Rong Ji’s lab has previously defined the pivotal role of TLRs in pain (Liu et al., 12).

Distinguished Professor of Anesthesiology, in the School of Medicine. Temugin Berta 1 *, Tong Liu 1, Yen-Chin Liu 1, 2, Zhen-Zhong Xu 1, Ru-Rong Ji 1 1 Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA , USA. From an evolutionary perspective, sensing danger is.

2 Department of Neurobiology, Duke University Medical Center, Durham, NC , USA.;. A nesthesiology ’s articles are made freely accessible to all readers, for personal use only, 6 months from the cover date of the issue. This led Ji to the lab of Yong-Hui Jiang, also at Duke, who had recently created genetically engineered mice lacking SHANK3;.

I stayed in Dr. During her Ph.D., she was a visiting scholar at Duke University, under the supervision of Dr. Ru-rong.ji@duke.edu Injury/insult Arthritis, nerve injury, cancer treatment Non-neuronal cells Immune and glial cells Other cells Nociceptors Pain modulation.

I joined the Knight Lab in 15, and I work in the wet lab where I assist our talented team in preparing samples for NGS applications. At UCI, Alessandra is studying the relevance of inflammatory and immune responses in the progression of Alzheimer’s disease. 3 Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science.

Here, I study neuron-cancer interaction as well as how cancer immunotherapy affects pain sensory. Alexander Chamessian 1, ;. I received my M.S.

Ru-Rong Ji, PhD Professor Departments of Anesthesiology, Cell Biology, and Neurobiology Director of Sensory Plasticity and Pain Research Laboratory Co-Director of Center for Translational Pain Medicine Ji lab studies molecular and cellular mechanisms of chronic pain using mouse models, electrophysiology, and cell biology assays. Martini joined the LaFerla lab in 15, to study the relevance of inflammatory and immune responses in the progression of Alzheimer’s disease. Ji gave a seminar on "Glial control of synaptic transmission and pain".

2 Department of Neurobiology, Duke University Medical Center, Durham, NC , USA.;. There are at least 30 different kinds of TRP, specialized to sense pain, itch, heat, cold, and other sensations and turn them into signals to the brain, said Ru-Rong Ji, Ph.D., a university distinguished professor of anesthesiology in the Duke School of Medicine who co-authored the study. Chronic pain is a major health problem in the US, affecting 100 million Americans.

As a first-year student, I'm currently doing my rotation in Dr. Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 0032, China. Nat Rev Drug Discov.

Ru Rong Ji, PhD, of the department of anesthesiology at Duke University School of Medicine, and his team conduct molecular, cellular and electrophysiological studies in human dorsal root ganglion (DRG) neurons. In this study, we examined the role of TLR9 in CIPN induced by paclitaxel in WT and Tlr9 mutant mice of both sexes. Serhan,2and Ru-Rong Ji1 1Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

The proinflammatory cytokine Interleukin-17 (IL-17) is produced mainly by Th17 cells and has been implicated in pain regulation. Ru-Rong Ji is a professor of Anesthesiology and Neurobiology, Chief of Pain Research at the Duke University Medical Center. Interested candidates should email their CV, a brief statement of interests, and a list of three references to Dr.

I then came to Duke Med to begin my medical education in 10. Volume 133, Issue 4. Ji was curious to see if the mice also had changes in pain perception, just like humans without the gene do.

Tong Liu, 1, 2, 5 Qingjian Han, 1, 5 Gang Chen, 1 Ya Huang, 2 Lin-Xia Zhao, 3 Temugin Berta, 1 Yong-Jing Gao, 3 and Ru-Rong Ji 1, 4. I am most interested in human-microbe interactions, especially in regard to the gut-brain axis. Publications700k+ research projects Join for free.

Third Year Mentor - Anesthesiology, Surgery, and Environmental Physiology Study Program (ASEP). Chronic pain is a major health problem in the US, affecting 100 million Americans. Address correspondence to Dr.

Currently, I am pursuing my PhD jointly with Dr Ru-Rong Ji in the Pain Signaling and Sensory Plasticity Laboratory and Dr Thomas Van de Ven in the Translational Pain Research Laboratory EDUCATION:. Ru-Rong Ji Lab, Duk Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like severe allergic reactions, acute-onset diabetes and heart damage. NIH Public Access Author Manuscript Nat Rev Drug Discov.

Ru-Rong Ji, PhDProfessor and Co-Director Before joining Duke University, he was a faculty at Harvard Medical School (1998-12). The main goal of the lab is to identify novel molecular and cellular mechanisms that underlie the genesis of chronic pain. Bo Tao from Johns Hopkins University joined Wu lab as a Research Assistant.

Ru-Rong Ji, PhD, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina,. Ru-Rong Ji 1, 2, *, ;. Chul-Kyu Park,1 Ning Lü,1 Zhen-Zhong Xu,1 Tong Liu,1 Charles N.

The checkpoint inhibitory protein PD-L1 inhibited acute inflammatory pain. Ru-rong.ji@duke.edu Chronic pain is a major health problem in the US, affecting 100 million Americans. Duke University Medical Center, Durham, North Carolina.

Ru-Rong Ji, PhD, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, , USA. And NS479 to R.-R.Ji. This is the second in a series of Forum interviews with PRF’s eight new science advisors for 14-15.

Brigham and Women's Hospital Department of Anesthesiology, Perioperative and Pain Medicine 75 Francis Street Boston, MA :. 1 Department of Anesthesiology, Duke University Medical Center, Durham, NC , USA.;. -- Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like severe.

Here we report that glia-produced IL-17 suppresses inhibitory synaptic transmission in spinal cord pain circuit and drives chemotherapy-induced neuropathic pain. From Saint Mary’s College of California. Close mobile search navigation.

Qingqing Wang's lab at Zhejiang University, China. Ru-Rong Ji Lab, Duke University Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like. Ru-Rong Ji 1 , Zhen-Zhong Xu 1 , Yong-Jing Gao 2 Affiliations 1 Departments of Anesthesiology and Neurobiology, Duke University Medical Center, 595 LaSalle Street, Durham, North Carolina , USA.

Ru-Rong Ji Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts , USA See all articles by this author. However, synaptic mechanisms by which IL-17 regulates pain transmission are unknown. These animals exhibit a number of ASD behaviors.

Available in PMC 14 November 12. The Ji lab is always recruiting talented postdoctoral fellows, visiting scholars, graduate students, and undergraduate students. Pharmacology & Cancer Biology Lab:.

Ru-Rong Ji, PhD Associate Professor of Anaesthesia, Harvard Medical School. Ru-Rong Ji Lab, Duke University. I received a BS in Biochemistry from Stony Brook University in 09.

Briana Davis - T32 Grant Funded 5T32GM Departmental Affiliation:. Find a Researcher Ru-Rong Ji, PhD. In the lab, they use human DRG tissue to study gene expression in human sensory neurons and test novel pain therapeutics.

The long-term goal of the lab is to identify molecular and cellular. Ru-Rong Ji, PhD, is the chief of pain research within Duke Anesthesiology, co-director of the Center for Translational Pain Medicine, and a professor of anesthesiology and neurobiology. Key Laboratory of Neuroregeneration of Jiangsu and the Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, , China.

All animal procedures were conducted in accordance with the NIH’s Guide for the Care and Use of Laboratory Animals (National Academies Press, 11). Pain Research Center, Department of Anesthesiology, University of Cincinnati Medical Center, Cincinnati, OH, , USA. 15-16 new awards include Warren Grill (Biomedical Engineering), Ru-Rong Ji (Anesthesiology), Nandan Lad (Surgery) for their project on.

Ru-Rong Ji and colleagues have reported a method for treating pain intended to help treat inflammatory pain, neuropathic pain, and cancer pain. Liam Lewis - T32 Grant Funded 5T32GM Departmental Affiliation:. In 18, I moved to Dr Ru-Rong Ji’s laboratory at the Duke University Center for Translational Pain Medicine, where I am pursuing studies to identify molecular mediators of pain and pain-related neuroinflammation, with a particular emphasis on neuron-cancer and neuron-glia interactions.

Pain is notoriously difficult to measure, but Ji said the new molecule may serve as a biomarker for pain. 4 Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical. They have uncovered programmed cell death ligand-1 (PD-L1) as an endogenous inhibitor of acute and chronic pain.

We employ a multidisciplinary approach that covers in vitro, ex vivo, and in vivo electrophysiology, cell biology of glial cells, immune cells, and cancer cells, transgenic mice, and mouse behaviors of various sensory. In Biology at Nanjing University in China and received his Ph.D. Liu was supported by grants from National Natural Science Foundation of China ( and.

Emerging studies indicate a sex-dimorphic role of Toll-like receptor 4 (TLR4) in driving neuropathic pain. Ru-Rong Ji, PhD, is distinguished professor and chief of pain research at Duke University Medical Center in Durham, North Carolina, US. Eight interdisciplinary research teams at Duke have been selected to receive the 15-16 Duke Institute for Brain Sciences (DIBS) Research Incubator Awards (five new awards and three continuation awards).

Ouyang Chen Departmental Affiliation:. The finding that the miRNA let-7b can rapidly activate nociceptors and induce pain via a pathway involving TLR7 and TRPA1 is astounding. In Biology from San Diego State University, and my B.S.

Affiliations 1 Department of Anesthesiology, Duke University Medical Center, Durham, NC , USA. Ru-Rong Ji Sensory neurons are activated by physical and chemical stimuli, eliciting sensations such as temperature, touch, pain, and itch. Published in final edited form as:.

Molecular Genetics & Microbiology Lab:. During that time, she also worked at Duke University, as a visiting scholar, under the supervision of Dr. “We’re also interested to know if targeting this miRNA would be a way to alleviate pain.” The study was supported by NIH grants R01-DE, R01-DE, and NS to Ru-Rong Ji and R21-NS985 to Zhen-Zhong Xu.

Here, they address the question of how miRNAs might excite nociceptors via TLR7. Chemotherapy-induced peripheral neuropathy (CIPN) remains a pressing clinical problem;. Ru-Rong Ji’s profile, publications, research topics, and co-authors.

The long-term goal of the lab is to identify molecular and cellular mechanisms that underlie the genesis of chronic pain and, furthermore, to develop novel pain therapeutics that can target these mechanisms. Prior to joining Duke, the main focus of my undergraduate research was autoimmune diseases. Currently he is a Distinguished Professor of Duke University and Co-Director of Center for Translational Pain Medicine.

Ji received his B.S. 3 Department of Anesthesiology, Duke University Medical Center, Durham, NC , USA.;. Serhan,2 and Ru-Rong Ji1 1Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, and 2Center for Experimental Therapeutics and Reperfusion Injury, Harvard Institutes of Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s.

CHICAGO - The American Society of Anesthesiologists (ASA) today presented Ru-Rong Ji, Ph.D., with its Excellence in Research Award in recognition of his extensive research career focused on.